A picture with more details is painted for prostate cancer
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منابع مشابه
A picture with more details is painted for prostate cancer.
B y comparing all gene-coding sequences in the genome between tumors and matched normal samples from clinically localized and castration-resistant (CR) prostate cancer patients, two groups of scientists have recently identified more than 5000 somatic mutations. These findings are important because they add another dimension of somatic DNA alterations in the genome of prostate tumors. Together w...
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Background: Radiotherapy and adjuvant androgen deprivation therapy have historically been the first treatment choices for prostate cancer but treatment resistance often limits the capacity to effectively manage the disease. Therefore, alternative therapeutic approaches are needed. Here, the efficacies of radiotherapy and targeting the pro-survival cell signaling components epidermal growth fact...
متن کاملp63 is more sensitive and specific than 34βE12 to differentiate adenocarcinoma of prostate from cancer mimickers
Objective(s): Prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. Differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. Considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...
متن کاملWhat is the most appropriate test in detecting prostate cancer in patients with intermediate prostate specific antigen levels?
Abstract Background: Regarding the variety of tests present for detecting and also screening prostate cancer and also bearing in mind the advantages and disadvantages of these tests we decided to re-evaluate these tests (total prostate specific antigen and all of its modifications) in detecting prostate cancer in men with intermediate serum PSAlevels. Methods: Following a cross se...
متن کاملp63 is more sensitive and specific than 34βe12 to differentiate adenocarcinoma of prostate from cancer mimickers
objective(s): prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...
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ژورنال
عنوان ژورنال: Asian Journal of Andrology
سال: 2012
ISSN: 1008-682X,1745-7262
DOI: 10.1038/aja.2012.73